Chest
Clinical InvestigationsQuality-of-Life Determinants in Patients With Clinically Stable Bronchiectasis
Section snippets
Study Population
The present study comprised all patients with bronchiectasis involving more than one lobe or cystic bronchiectasis not attributable to cystic fibrosis (CF) in our center during the period between 1990 and June 2003. Patients with traction bronchiectasis due to severe emphysema or advanced fibrosis were excluded, as were those presenting with surgically treated bronchiectasis or chronic background diseases sufficiently serious to interfere with patient quality of life to a greater extent than
Results
A total of 132 patients had bronchiectasis involving more than one lobe or cystic bronchiectasis not attributable to CF during the prospective study period. Fifteen patients with traction bronchiectasis were excluded, along with 14 patients with severe pathology causing greater quality-of-life deterioration than the actual bronchial disease, 13 subjects with manifest physical or psychological incapacity to follow the study protocol, 2 patients with surgically treated bronchiectasis, and 2
Discussion
In our series, dyspnea, the FEV1value following bronchodilation, and daily sputum production were the most relevant HRQL-conditioning variables among the patients with non-CF SB, although other symptoms such as the presence of habitual coughing or wheezing also exerted a relative influence.
The SGRQ was designed by Jones et al7a little over a decade ago for specific application to COPD and other obstructive pulmonary diseases.16, 17, 18, 19, 20 In 1997, Wilson et al 8 validated the English
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This study was supported in party by the grant RedRespira-ISCiii-TRIC-03/11 from the Ministerio de Sanidad y Consumo, Spain.
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