Chest
Volume 129, Issue 2, February 2006, Page 494
CorrespondenceCO2 Can Be Good for You
Section snippets
To the Editor
The study of the effects of noninvasive positive pressure ventilation to reduce chronic compensated CO2 retention in COPD patients1 ignores the possible adaptive advantage of “resetting” the Pco2 to a higher level than normal. As experts in the mechanics of COPD have argued in the past, chronic compensated CO2 retention will allow for CO2 homeostasis at a lower level of alveolar, and thus minute, ventilation. This may result in decreased dyspnea during exercise.23 Some time ago, we reported on
References (4)
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Outcome of patients with stable COPD receiving controlled positive pressure ventilation aimed at a maximal reduction of Paco2
Chest
(2005) The adaptive function of hypercapnia
(1978)
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Copyright © 2006 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.