Chest
Original ResearchImpact of Pulmonary Rehabilitation on Psychosocial Morbidity in Patients With Severe COPD
Section snippets
Patients
We enrolled consecutive eligible patients with COPD1 at our outpatient clinic. Inclusion criteria were as follows: age ≤ 75 years; FEV1 < 70% of reference values; FEV1/FVC ratio < 65%, Pao2 > 55 mm Hg at rest, no indications for home oxygen therapy, and no exacerbation or hospitalization in the previous 2 months. Exclusion criteria were psychiatric disturbances, heart disease, or relevant bone or joint disease. The hospital ethics committee approved the study, and all patients provided written
Results
We randomized 40 male patients aged 65 ± 8 years (mean ± SD). All patients had severe chronic airflow limitation with FEV1 of 35 ± 13% of the reference value and without respiratory failure (Pao2, 72 ± 9 mm Hg; Paco2, 42 ± 5 mm Hg). Five patients withdrew from the study, two patients in the PRG and one patient in the CG as the result of exacerbation during the first month; and two patients from the CG decided to abandon the study during the first weeks. The PRG was therefore made up of 18
Discussion
This study suggests that PR without a specific psychological intervention program can impact positively on psychosocial morbidity in patients with COPD. We found substantial differences between groups in favor of the PRG on some, but not all, domains of two questionnaires that address issues of psychosocial morbidity. In the questionnaire domains that failed to show significant differences, most favored the intervention group.
COPD is a progressive irreversible disease that, in its advanced
Acknowledgment
The authors thank Carolyn Newey for help with editing the text.
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Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).
Preliminary results were presented at the ERS Congress, Geneva, Switzerland, 1998.
Supported in part by RTIC-ISC-III-Red Respira, SEPAR.