Chest
Evaluation of the Progress and Prognosis of Adult Respiratory Distress Syndrome: Simple Respiratory Physiologic Measurement
Section snippets
MATERIALS AND METHODS
We studied 14 consecutive patients who developed acute respiratory failure and were treated in the intensive care unit at the Osaka University Hospital between April, 1974 and April, 1977. All fulfilled the following criteria: 1) no apparent prior pulmonary disorders prior to shock, trauma, or surgical stress; 2) marked hypoxemia (P[A-a]O2 of more than 500 mm Hg); 3) diffuse bilateral infiltrates without cardiac enlargement on chest films; 4) clinical signs of respiratory distress, such as
RESULTS
Of the 14 patients with ARDS, four recovered from acute respiratory failure. The over-all mortality was 71.4 percent.
DISCUSSION
There is a wide variety of studies concerning the pathology and pathophysiology of ARDS. Still there are a great number of patients who develop acute respiratory failure in the intensive care unit. The mortality rate for these patients is remarkably high. The lack of definite criteria of ARDS makes the precise evaluation of the results of experimental and clinical studies difficult. We have selected 14 consecutive patients who developed acute hypoxemia (P[A-a]O2 of more than 500 mm Hg) within
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Manuscript received September 5; revision accepted December 5.