Pulmonary migratory infiltrates and pachypleuritis in a patient with Crohn's disease

Respiration. 2000;67(4):459-63. doi: 10.1159/000029550.

Abstract

Crohn's disease can be associated with several respiratory manifestations. We report here a case of pulmonary migratory infiltrates associated with bilateral pleural thickening and peripheral eosinophilia. The histopathological findings show an association of necrotizing nodules, eosinophilic infiltration in the non-abscessed lung tissue, areas of non-caseating epithelioid granulomas, and an extensive pleural fibrosis. The different histopathological findings are detailed and the responsibility of either Crohn's disease or treatment by mesalazine is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Crohn Disease / complications*
  • Crohn Disease / drug therapy
  • Eosinophilia / complications
  • Female
  • Humans
  • Lung / pathology
  • Lung Diseases / complications*
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology
  • Mesalamine / therapeutic use
  • Pleurisy / complications*
  • Pleurisy / diagnostic imaging
  • Pleurisy / pathology
  • Radiography, Thoracic
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Mesalamine