Extracorporeal membrane oxygenation: a ten-year experience

Am J Surg. 2000 Aug;180(2):144-54. doi: 10.1016/s0002-9610(00)00432-3.

Abstract

Background: Extracorporeal membrane oxygenation (ECMO) is a supportive therapy used for severe acute respiratory distress syndrome (ARDS). We present outcome, clinical parameters, and complications in a cohort of 245 ARDS patients of whom 62 were treated with ECMO.

Methods: Data of all ARDS patients were prospectively collected between 1991 and 1999. Outcome and clinical parameters of patients treated with and without ECMO were evaluated.

Results: One hundred thirty-eight patients were referred from other hospitals, 107 were primarily located in our hospital. About one fourth of these patients were treated with ECMO. The survival rate was 55% in ECMO patients and 61% in non-ECMO patients.

Conclusions: ECMO is a therapeutic option for patients with severe ARDS, likely to increase survival. However, a randomized controlled study proving its benefit is still awaited. Until the development of a causal or otherwise superior therapy ECMO should be used in selected patients.

Publication types

  • Review

MeSH terms

  • Adult
  • Extracorporeal Membrane Oxygenation*
  • Female
  • Humans
  • Male
  • Respiratory Distress Syndrome / therapy*
  • Treatment Outcome