Abstract
Infection associated with an indwelling catheter is a representative type of biofilm infection occurring in the urinary tract. Since the most effective way to control this intractable infection is the prevention of bacterial attachment and subsequent biofilm formation on the catheter, the importance of catheter materials and anti-bacterial coating cannot be underestimated. The difference in the degree of bacterial attachment among standard catheter materials, the efficacy of silver-coating of catheters in preventing infection and the potency and effectiveness of a new lecithin/silver coating are discussed.
MeSH terms
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Anti-Infective Agents, Urinary / pharmacology*
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Anti-Infective Agents, Urinary / therapeutic use
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Bacterial Adhesion
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Biofilms / drug effects
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Biofilms / growth & development*
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Catheters, Indwelling / adverse effects*
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Catheters, Indwelling / microbiology
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Gram-Negative Bacteria / growth & development
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Gram-Negative Bacteria / ultrastructure
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Gram-Negative Bacterial Infections / urine
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Humans
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Microscopy, Electron, Scanning
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Phosphatidylcholines / metabolism
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Silicones / metabolism
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Silver Compounds / metabolism
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Urinary Catheterization / adverse effects*
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Urinary Tract Infections / microbiology
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Urinary Tract Infections / prevention & control*
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Urinary Tract Infections / urine
Substances
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Anti-Infective Agents, Urinary
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Phosphatidylcholines
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Silicones
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Silver Compounds