Dramatic decrease in the pulmonary artery systolic pressure and disappearance of the interatrial shunt with sildenafil treatment in a patient with primary pulmonary hypertension with atrial septal aneurysm and a severe right to left shunt through the patent foramen ovale

Osman Karakaya; Nihal Ozdemir; Cihangir Kaymaz; Irfan Barutcu

doi:10.1016/j.ijcard.2005.05.076

Dramatic decrease in the pulmonary artery systolic pressure and disappearance of the interatrial shunt with sildenafil treatment in a patient with primary pulmonary hypertension with atrial septal aneurysm and a severe right to left shunt through the patent foramen ovale

Int J Cardiol. 2006 Jun 7;110(1):97-9. doi: 10.1016/j.ijcard.2005.05.076. Epub 2006 Feb 28.

Authors

Osman Karakaya, Nihal Ozdemir, Cihangir Kaymaz, Irfan Barutcu

PMID: 16507322
DOI: 10.1016/j.ijcard.2005.05.076

Abstract

This report describes a patients with PPH with atrial septal aneurysm and a severe right to left shunt through the patent foramen ovale who showed a dramatic decrease in the pulmonary artery systolic pressure and interatrial shunt disappeared after sildenafil treatment.

Publication types

Case Reports
Letter

MeSH terms

3',5'-Cyclic-GMP Phosphodiesterases / antagonists & inhibitors
Adult
Blood Pressure / drug effects*
Echocardiography, Transesophageal
Female
Heart Aneurysm / diagnostic imaging
Heart Aneurysm / drug therapy*
Heart Aneurysm / physiopathology
Heart Septal Defects, Atrial / diagnostic imaging
Heart Septal Defects, Atrial / drug therapy*
Heart Septal Defects, Atrial / physiopathology
Humans
Hypertension, Pulmonary / diagnostic imaging
Hypertension, Pulmonary / drug therapy*
Hypertension, Pulmonary / physiopathology
Piperazines / therapeutic use*
Pulmonary Artery / diagnostic imaging
Pulmonary Artery / physiopathology*
Pulmonary Circulation
Purines
Sildenafil Citrate
Sulfones
Vasodilator Agents / therapeutic use*

Substances

Piperazines
Purines
Sulfones
Vasodilator Agents
Sildenafil Citrate
3',5'-Cyclic-GMP Phosphodiesterases