Objective: To determine whether the results of functional residual capacity measurements after endotracheal suctioning could guide the decision to perform an alveolar recruitment maneuver and thus improve lung function.
Design: Prospective, randomized, controlled interventional study.
Setting: Intensive care unit of a university hospital.
Patients: Fifty-nine mechanically ventilated patients within 2 hrs after elective cardiac surgery without preexisting lung diseases.
Interventions: Patients received a standard suctioning procedure with disconnection of the ventilator (20 secs, 14 F catheter, 200 cm H2O negative pressure). Prospectively, patients were stratified into two groups by the postsuctioning functional residual capacity value (group A: functional residual capacity >94% of baseline; group B: functional residual capacity <94% of baseline). Both groups were randomized into either a recruitment maneuver (RM) group (positive end-expiratory pressure 15 cm H2O, peak inspiratory pressure 35-40 cm H2O for 30 secs, group RM) or a non-RM group, in which ventilation was resumed without an RM (group NRM), resulting in four groups.
Measurements and main results: Functional residual capacity and arterial blood gases were recorded for up to 1 hr. In addition, distribution of ventilation was measured by means of electrical impedance tomography. The RM had an impact on distribution of ventilation, functional residual capacity, and oxygenation in patients with a decrease of functional residual capacity after suctioning. In contrast, the RM showed no impact on these parameters in patients with no decrease of functional residual capacity after suctioning.
Conclusions: By measurements of functional residual capacity after endotracheal suctioning, patients profiting from a consecutive recruitment maneuver could be identified. Guiding the recruitment strategy on changes of functional residual capacity may improve patient care.
Trial registration: ClinicalTrials.gov NCT00779090.