The Past, Present, and Future of Nicotine Addiction Therapy

Annu Rev Med. 2016:67:467-86. doi: 10.1146/annurev-med-111314-033712. Epub 2015 Aug 26.

Abstract

The tobacco addiction treatment field is progressing through innovations in medication development, a focus on precision medicine, and application of new technologies for delivering support in real time and over time. This article reviews the evidence for combined and extended cessation pharmacotherapy and behavioral strategies including provider advice, individual counseling, group programs, the national quitline, websites and social media, and incentives. Healthcare policies are changing to offer cessation treatment to the broad population of smokers. With knowledge of the past and present, this review anticipates what is likely on the horizon in the clinical and public health effort to address tobacco addiction.

Keywords: cessation; cigarette; quitline; smoking; tobacco; vape.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Alkaloids / therapeutic use
  • Azocines / therapeutic use
  • Bupropion / therapeutic use
  • Directive Counseling
  • Dopamine Uptake Inhibitors / therapeutic use
  • Drug Therapy, Combination
  • Health Policy
  • Humans
  • Nicotine / administration & dosage*
  • Nicotine / adverse effects*
  • Nicotine / antagonists & inhibitors
  • Nicotine / metabolism
  • Nicotinic Agonists / therapeutic use
  • Quinolizines / therapeutic use
  • Smoking Cessation / methods*
  • Social Media
  • Text Messaging
  • Tobacco Use Cessation Devices*
  • Tobacco Use Disorder / etiology
  • Tobacco Use Disorder / therapy*
  • Varenicline / therapeutic use

Substances

  • Alkaloids
  • Azocines
  • Dopamine Uptake Inhibitors
  • Nicotinic Agonists
  • Quinolizines
  • Bupropion
  • cytisine
  • Nicotine
  • Varenicline