In a multicenter group comparative study with 51 patients suffering from chronic obstructive lung diseases, efficacy and tolerance of physiotherapy with the VRP1 Desitin was investigated. In comparison with the control group (concomitant respiratory physiotherapy) a statistically significant increase in the lung function parameter VC, FEV1 and PEF was demonstrated in the VRP1 Desitin-group after 2 weeks of investigation. Auscultatory findings as well as the clinical symptoms cough, sputum and dyspnea were clearly improved. The patients observed an improvement in their condition and capability.