Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Background This systematic review and meta-analysis summarizes the safety and efficacy
of high flow nasal cannula (HFNC) in patients with acute hypoxemic respiratory failure. …

Background The efficacy of venovenous extracorporeal membrane oxygenation (ECMO) in
patients with severe acute respiratory distress syndrome (ARDS) remains controversial. …

This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2018. Other selected articles can be found online at https://www.…

The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the
European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult …

A prospective, crossover, physiologic study was performed in 10 patients with acute lung
injury to assess the respective short-term effects of noninvasive pressure-support ventilation …

Methods All consecutive patients with acute respiratory failure and laboratory-confirmed
SARS-CoV-2 infection admitted to one of the four participating dedicated COVID-19 ICUs in …

Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is
associated with poor clinical outcomes. Although the importance and impact of lung-protective …

Rationale: Intensive care unit (ICU)- and mechanical ventilation (MV)-acquired limb muscle
and diaphragm dysfunction may both be associated with longer length of stay and worse …

Objective Noninvasive ventilation (NIV) fails more frequently for de novo acute respiratory
failure (de novo) than for cardiogenic pulmonary edema (CPE) or acute-on-chronic respiratory …