Background Nontuberculous Mycobacterium infections, particularly Mycobacterium abscessus,
are increasingly common among patients with cystic fibrosis and chronic bronchiectatic …

The 6-minute-walk test is a commonly used assessment of performance ability in a variety of
cardiopulmonary diseases. It provides important functional information that is not captured …

BACKGROUND: Optimal timing of mechanical ventilation in COVID-19 is uncertain. We sought
to evaluate outcomes of delayed intubation and examine the ROX index (ie, [ S pO 2 /F IO …

The number of waitlisted lung transplant candidates exceeds the availability of donor organs.
Barriers to utilization of donor lungs include suboptimal lung allograft function, long …

Importance Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with
poor prognosis. Approved therapies do not halt disease progression. Objective To determine …

Purpose The outcomes of patients requiring invasive mechanical ventilation for COVID-19
remain poorly defined. We sought to determine clinical characteristics and outcomes of …

… Optimal CF care requires a multidisciplinary team at a center experienced in caring for this …
to care at an accredited center may not always be immediately available. An analysis of 1,249 …

… in patients with a baseline ordinal score of 5, we performed a subgroup analysis in those
enrolled with a baseline ordinal score of 6 or 7, which suggested a trend toward reduced …

… 2 study were eligible to participate in an open-label extension study to assess long-term
safety and efficacy of PRM-151. Here we present an analysis of the safety and efficacy with up to …

Background Recombinant human pentraxin-2 (rhPTX-2) significantly decreased decline in
percent predicted forced vital capacity (FVC) and stabilized 6-min walk distance (6MWD) in …