Guaifenesin has no effect on sputum volume or sputum properties in adolescents and adults with acute respiratory tract infections

A Hoffer-Schaefer, HJ Rozycki, MA Yopp… - Respiratory …, 2014 - rc.rcjournal.com
BACKGROUND: Guaifenesin (glyceryl guaiacolate ether [GGE]) has been studied as a cough
suppressant and as an expectorant; however, published studies to date have failed to find …

IL-33 Increases IL-8 Secretion From Human Airway Goblet Cells

…, S Kanoh, A Hoffer-Schaefer… - A36. CYTOKINES …, 2012 - atsjournals.org
Results: With PBS, IL-8 was secreted from the apical side of goblet cells (> 100 x basolateral
secretion) and ciliated cells (> 5 x basolateral). IL-13 induced ST2R mRNA  from goblet …

Secretory Phospholipases A2 Are Produced In Ciliated Airway Cells And Increase Goblet Cell MUC5AC

…, S Kanoh, A Hoffer-Schaefer… - D75. MUCINS …, 2012 - atsjournals.org
Methods: NHBE cells were grown for 14 days at air-liquid interface (ALI) with vehicle (ciliated
phenotype) or IL-13 to produce a goblet cell phenotype. Synthesis of sPLA subtypes Ib, IIa, …

Severe Human Metapneumovirus and Group A Streptococcus Pneumonia in an Immunocompetent Adult

HM Biggs, CA Van Beneden, K Kurkjian… - Clinical Infectious …, 2020 - academic.oup.com
An immunocompetent adult with asthma developed severe human metapneumovirus (HMPV)
illness complicated by group A Streptococcus coinfection, progressing to acute respiratory …