Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality
T Mauri, G Bellani, N Patroniti, A Coppadoro… - Intensive care …, 2010 - Springer
Purpose Pentraxin 3 (PTX3) is an inflammatory mediator produced by neutrophils,
macrophages, myeloid dendritic and endothelial cells. During sepsis a massive inflammatory …
macrophages, myeloid dendritic and endothelial cells. During sepsis a massive inflammatory …
Estimation of patient's inspiratory effort from the electrical activity of the diaphragm
G Bellani, T Mauri, A Coppadoro, G Grasselli… - Critical care …, 2013 - journals.lww.com
Objectives: To calculate an index (termed Pmusc/Eadi index) relating the pressure generated
by the respiratory muscles (Pmusc) to the electrical activity of the diaphragm (Eadi), during …
by the respiratory muscles (Pmusc) to the electrical activity of the diaphragm (Eadi), during …
[HTML][HTML] Noninvasive respiratory support outside the intensive care unit for acute respiratory failure related to coronavirus-19 disease: a systematic review and meta …
Background Noninvasive respiratory support (NIRS) has been diffusely employed outside
the intensive care unit (ICU) to face the high request of ventilatory support due to the massive …
the intensive care unit (ICU) to face the high request of ventilatory support due to the massive …
[HTML][HTML] Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak
Background Respiratory failure due to COVID-19 pneumonia is associated with high mortality
and may overwhelm health care systems, due to the surge of patients requiring advanced …
and may overwhelm health care systems, due to the surge of patients requiring advanced …
Pentraxin 3 in acute respiratory distress syndrome: an early marker of severity
T Mauri, A Coppadoro, G Bellani, M Bombino… - Critical care …, 2008 - journals.lww.com
Objective: Pentraxin 3 is a fluid phase receptor involved in innate immunity. It belongs to the
Pentraxins family, as C-reactive protein does. Pentraxin 3 is produced by a variety of tissue …
Pentraxins family, as C-reactive protein does. Pentraxin 3 is produced by a variety of tissue …
Topographic distribution of tidal ventilation in acute respiratory distress syndrome: effects of positive end-expiratory pressure and pressure support
…, P Tagliabue, M Turella, A Coppadoro… - Critical care …, 2013 - journals.lww.com
Objective: Acute respiratory distress syndrome is characterized by collapse of gravitationally
dependent lung regions that usually diverts tidal ventilation toward nondependent regions. …
dependent lung regions that usually diverts tidal ventilation toward nondependent regions. …
[HTML][HTML] Do spontaneous and mechanical breathing have similar effects on average transpulmonary and alveolar pressure? A clinical crossover study
…, G Grasselli, M Teggia-Droghi, T Mauri, A Coppadoro… - Critical care, 2016 - Springer
Background Preservation of spontaneous breathing (SB) is sometimes debated because it
has potentially both negative and positive effects on lung injury in comparison with fully …
has potentially both negative and positive effects on lung injury in comparison with fully …
A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretions
L Berra, A Coppadoro, EA Bittner, T Kolobow… - Critical care …, 2012 - journals.lww.com
Objective: We evaluated a new device designed to clean the endotracheal tube in mechanically
ventilated patients, the Mucus Shaver. Design: Prospective, randomized trial. Setting: …
ventilated patients, the Mucus Shaver. Design: Prospective, randomized trial. Setting: …
[HTML][HTML] Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data
…, RD Hubmayr, O Gajic, F Uhle, A Coppadoro… - Intensive care …, 2018 - Springer
Purpose The soluble receptor for advanced glycation end-products (sRAGE) is a marker of
lung epithelial injury and alveolar fluid clearance (AFC), with promising values for assessing …
lung epithelial injury and alveolar fluid clearance (AFC), with promising values for assessing …
[HTML][HTML] Novel preventive strategies for ventilator-associated pneumonia
Ventilator-associated pneumonia (VAP) is a complication of mechanical ventilation and is
defined as the occurrence of pneumonia in patients undergoing mechanical ventilation for at …
defined as the occurrence of pneumonia in patients undergoing mechanical ventilation for at …