User profiles for Antonio Gomez

Antonio Gomez, PhD

Senior Bioinformatician
Verified email at vhir.org
Cited by 6582

Distinct DNA methylomes of newborns and centenarians

…, S Moran, DG Pisano, A Gomez… - Proceedings of the …, 2012 - National Acad Sciences
Human aging cannot be fully understood in terms of the constrained genetic setting. Epigenetic
drift is an alternative means of explaining age-associated alterations. To address this …

Comparative evaluation of compact photobioreactors for large-scale monoculture of microalgae

AS Mirón, AC Gomez, FG Camacho, EM Grima… - Progress in industrial …, 1999 - Elsevier
Engineering analyses combined with experimental observations in horizontal tubular
photobioreactors and vertical bubble columns are used to demonstrate the potential of …

Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion

…, AM Rozeboom, BT Harris, E Blommaert, A Gomez… - Nature, 2021 - nature.com
Immune exclusion predicts poor patient outcomes in multiple malignancies, including triple-negative
breast cancer (TNBC) 1 . The extracellular matrix (ECM) contributes to immune …

DNA methylation contributes to natural human variation

…, I Hernando-Herraez, S Sayols, A Gomez… - Genome …, 2013 - genome.cshlp.org
DNA methylation patterns are important for establishing cell, tissue, and organism phenotypes,
but little is known about their contribution to natural human variation. To determine their …

Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming

…, F Serra, B Di Stefano, F Le Dily, J Quilez, A Gomez… - Nature …, 2018 - nature.com
Chromosomal architecture is known to influence gene expression, yet its role in controlling
cell fate remains poorly understood. Reprogramming of somatic cells into pluripotent stem …

[PDF][PDF] A prognostic DNA methylation signature for stage I non-small-cell lung cancer

…, S Moran, H Heyn, M Vizoso, A Gomez… - Journal of clinical …, 2013 - iris.unito.it
Purpose Non–small-cell lung cancer (NSCLC) is a tumor in which only small improvements
in clinical outcome have been achieved. The issue is critical for stage I patients for whom …

Radiologic evaluation of breast disorders related to pregnancy and lactation

JM Sabate, M Clotet, S Torrubia, A Gomez… - Radiographics, 2007 - pubs.rsna.org
During pregnancy and lactation, the breast can be affected by a variety of specific and unique
disorders, including benign disorders closely related to physiologic changes, inflammatory …

Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis

…, A Jauregui, S Ke, K Vessel, A Gomez… - The lancet respiratory …, 2022 - thelancet.com
Background Two acute respiratory distress syndrome (ARDS) subphenotypes (hyperinflammatory
and hypoinflammatory) with distinct clinical and biological features and differential …

Producing drugs from marine sponges

EH Belarbi, AC Gómez, Y Chisti, FG Camacho… - Biotechnology …, 2003 - Elsevier
Marine sponges are potential sources of many unique metabolites, including cytotoxic and
anticancer compounds. Natural sponge populations are insufficient or inaccessible for …

DNA methylation map of human atherosclerosis

…, E Condom, J Ramírez-Ruz, A Gomez… - Circulation …, 2014 - Am Heart Assoc
Background— Epigenetic alterations may contribute to the development of atherosclerosis.
In particular, DNA methylation, a reversible and highly regulated DNA modification, could …