All members of the higher education community share the important goal of fostering
college students' motivation to learn. Which contemporary constructs best explain students' …

Background Previous trials have shown that pridopidine might reduce motor impairment in
patients with Huntington's disease. The aim of this study was to ascertain whether higher …

Determining a molecule’s mechanism of action is paramount during chemical probe
development and drug discovery. The cellular thermal shift assay (CETSA) is a valuable tool to …

The neurodegenerative disease spinocerebellar ataxia type 1 (SCA1) is known to lead to
the progressive degeneration of specific neuronal populations, including cerebellar Purkinje …

Cellular thermal shift assay (CETSA) is a valuable method to confirm target engagement
within a complex cellular environment, by detecting changes in a protein’s thermal stability …

Effective sensory processing depends on sensory experience-dependent metaplasticity,
which allows homeostatic maintenance of neural network activity and preserves feature …

This report examines retail purchase data for 12 dairy products and margarine from the Nielsen
2007 Homescan data. Selected demographic and socioeconomic variables included in …

The confirmation of a small molecule binding to a protein target can be challenging when
switching from biochemical assays to physiologically relevant cellular models. The cellular …

Amyloid accumulation in Alzheimer’s disease (AD) is associated with synaptic damage and
altered connectivity in brain networks. While measures of amyloid accumulation and …

Introduction Individuals with cervical dystonia (CD) often report difficulty with balance and an
altered perception of vertical. Previous studies have suggested a decreased proprioceptive …