In this review, we compare the reported values of Young's modulus (YM) obtained from
indentation and tensile deformations of soft biological tissues. When the method of deformation is …

Glaucoma is a devastating neurodegenerative disease, which can lead to vision loss and is
associated with irreversible damage to retinal ganglion cells. Although the mechanism of …

Cardiovascular disease (CVD) remains a leading cause of death both within the United
States (US) as well as globally. In 2006 alone, over one-third of all deaths in the US were …

The influence of nucleus shape and orientation on the elastic modulus of epithelial cells was
investigated with atomic force microscopy. The shape and orientation were controlled by …

We have measured the force between a weakly charged micron-sized colloidal particle and
flat substrate in the presence of highly charged nanoparticles of the same sign under …

A topographically patterned substrate with stochastic surface order that closely mimics the
topographic features of native basement membranes has been fabricated to investigate the …

Purpose.: To determine the impact of substratum compliance and latrunculin-B (Lat-B), both
alone and together, on fundamental human trabecular meshwork (HTM) cell behavior. Lat-B …

We describe measurements of the scattering of visible light from an evanescent field by both
spherical particles (R = 1−10 μm) that are glued to atomic force microscopy (AFM) …

A growing body of literature broadly documents that a wide array of fundamental cell
behaviors are modulated by the physical attributes of the cellular microenvironment, yet in vitro …

The basement membrane of the corneal epithelium presents biophysical cues in the form of
topography and compliance that can modulate cytoskeletal dynamics, which, in turn, can …