User profiles for C. W. Seymour

Christopher W. Seymour

Associate Professor
Verified email at pitt.edu
Cited by 58963

The third international consensus definitions for sepsis and septic shock (Sepsis-3)

M Singer, CS Deutschman, CW Seymour… - Jama, 2016 - jamanetwork.com
Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function, …

[HTML][HTML] Time to treatment and mortality during mandated emergency care for sepsis

CW Seymour, F Gesten, HC Prescott… - … England Journal of …, 2017 - Mass Medical Soc
Background In 2013, New York began requiring hospitals to follow protocols for the early
identification and treatment of sepsis. However, there is controversy about whether more rapid …

A framework for the development and interpretation of different sepsis definitions and clinical criteria

DC Angus, CW Seymour, CM Coopersmith… - Critical care …, 2016 - journals.lww.com
… Angus and Seymour and were supported, in part, by grants from the National Institutes of
Health (NIH) (GM104022, GM107650, and HL123020). Dr. Seymour received support for …

Developing a new definition and assessing new clinical criteria for septic shock: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis …

M Shankar-Hari, GS Phillips, ML Levy, CW Seymour… - Jama, 2016 - jamanetwork.com
Importance Septic shock currently refers to a state of acute circulatory failure associated with
infection. Emerging biological insights and reported variation in epidemiology challenge the …

[HTML][HTML] Redefining critical illness

…, JP Reilly, JA Russell, JE Sevransky, CW Seymour… - Nature medicine, 2022 - nature.com
Research and practice in critical care medicine have long been defined by syndromes,
which, despite being clinically recognizable entities, are, in fact, loose amalgams of …

[HTML][HTML] The global burden of sepsis: barriers and potential solutions

…, S Bory, B Mutahunga, CW Seymour… - Critical care, 2018 - Springer
Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases
and deaths are estimated to occur in low and middle-income countries. Barriers to reducing …

[HTML][HTML] Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016

…, M Ranieri, CA Schorr, MA Seckel, CW Seymour… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Assessment of clinical criteria for sepsis: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

CW Seymour, VX Liu, TJ Iwashyna, FM Brunkhorst… - Jama, 2016 - jamanetwork.com
… Dr Seymour reports receipt of personal fees from Beckman Coulter. Dr Singer reports
board memberships with InflaRx, Bayer, Biotest, and Merck. Dr Deutschman reports holding …

[HTML][HTML] Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

…, FR Machado, KK Reinhart, K Rowan, CW Seymour… - The Lancet, 2020 - thelancet.com
Background Sepsis is life-threatening organ dysfunction due to a dysregulated host response
to infection. It is considered a major cause of health loss, but data for the global burden of …

Interleukin-6 receptor antagonists in critically ill patients with Covid-19–preliminary report

…, MS Santos, CT Saunders, CW Seymour… - Medrxiv, 2021 - medrxiv.org
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …