Rationale: Significant progress has been made in understanding the pathogenesis of acute
respiratory distress syndrome (ARDS). Recent advances in hospital practice may have …

Background Sepsis is a major risk factor for the development of thrombocytopenia, but few
studies have specifically evaluated prognostic importance of thrombocytopenia in patients …

Pregnancy is associated with many physiologic and hormonal changes along with changes
in sleep architecture, placing pregnant women at risk for the development of sleep-…

Background: To improve the safety of ventilator care and decrease the risk of ventilator-induced
lung injury, we designed and tested an electronic algorithm that incorporates patient …

OBJECTIVE To describe the clinical course and outcome of adults hospitalized with the
2009 H1N1 influenza infection. PATIENTS AND METHODS In this retrospective study, we …

Objective Hypotension following endotracheal intubation in the ICU is associated with poor
outcomes. There is no formal prediction tool to help estimate the onset of this hemodynamic …

Background There are limited data regarding the development of myocardial dysfunction
after a traumatic brain injury (TBI). We investigated incidence, risk factors, and prognostic …

Background Providing analgesia and sedation is an essential component of caring for many
mechanically ventilated patients. The selection of analgesic and sedative medications …

Background: Little is known about hypoxemia surrounding endotracheal intubation in the
critically ill. Thus, we sought to identify risk factors associated with peri-intubation hypoxemia …

OBJECTIVES: To describe the prevalence, associated risk factors, and outcomes of serious
neurologic manifestations (encephalopathy, stroke, seizure, and meningitis/encephalitis) …