User profiles for Charles G Irvin

Charles Irvin

Professor, University of Vermont
Verified email at med.uvm.edu
Cited by 32835

An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications

RA Dweik, PB Boggs, SC Erzurum, CG Irvin… - American journal of …, 2011 - atsjournals.org
Background: Measurement of fractional nitric oxide (NO) concentration in exhaled breath (Fe
NO ) is a quantitative, noninvasive, simple, and safe method of measuring airway …

Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors …

…, JL Hankinson, CG Irvin… - American …, 2000 - researchinformation.amsterdamumc …
… Casaburi, AL Coates, PL Enright, JL Hankinson, CG Irvin, NR MacIntyre, RT McKay, JS
Wanger, SD Anderson, DW Cockcroft, JE Fish, PJ Sterk …

TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice

…, S Kapadia, A Logar, A Henry, CG Irvin… - The Journal of …, 2008 - journals.aai.org
Steroid-resistant asthma comprises an important source of morbidity in patient populations.
TH 17 cells represent a distinct population of CD4+ Th cells that mediate neutrophilic …

Defining a link with asthma in mice congenitally deficient in eosinophils

…, D Colbert, L Rinaldi, SJ Ackerman, CG Irvin… - Science, 2004 - science.org
Eosinophils are often dominant inflammatory cells present in the lungs of asthma patients.
Nonetheless, the role of these leukocytes remains poorly understood. We have created a …

[HTML][HTML] Role of IL-6 in asthma and other inflammatory pulmonary diseases

M Rincon, CG Irvin - International journal of biological sciences, 2012 - ncbi.nlm.nih.gov
The incidence and severity of chronic lung diseases is growing and affects between 100
and 150 million people worldwide and is associated with a significant rate of mortality. …

[HTML][HTML] Measuring the lung function in the mouse: the challenge of size

CG Irvin, JHT Bates - Respiratory research, 2003 - Springer
Measurement of the effects of drugs, mediators and infectious agents on various models of
lung disease, as well as assessment of lung function in the intact mouse has the potential for …

Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation

…, D Raymond, ME Poynter, JY Bunn, CG Irvin - Journal of Allergy and …, 2011 - Elsevier
BACKGROUND: Asthma in obese subjects is poorly understood, and these patients are
often refractory to standard therapy. OBJECTIVES: We sought to gain insights into the …

Technical standards for respiratory oscillometry

…, R Farré, GL Hall, I Ioan, CG Irvin… - European …, 2020 - Eur Respiratory Soc
Oscillometry (also known as the forced oscillation technique) measures the mechanical
properties of the respiratory system (upper and intrathoracic airways, lung tissue and chest wall) …

Obesity and asthma: an inflammatory disease of adipose tissue not the airway

…, RE Pratley, P Forgione, O Dienz, CG Irvin… - American journal of …, 2012 - atsjournals.org
Rationale: Obesity is a major risk factor for asthma; the reasons for this are poorly understood,
although it is thought that inflammatory changes in adipose tissue in obesity could …

Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population

…, N Hizawa, M Taniguchi, JJ Lima, CG Irvin… - Nature …, 2011 - nature.com
Bronchial asthma is a common inflammatory disease caused by the interaction of genetic
and environmental factors 1 , 2 . Through a genome-wide association study and a replication …