BACKGROUND: The objective of this study was to determine whether the implementation of
an inhaled nitric oxide protocol (INO) in a pediatric ICU (PICU) would reduce cost …

Epstein–Barr Virus-transformed B lymphoblastoid cell lines (EBV-LCLs) are routinely used
for the in vitro expansion of T cells. However, these cell lines are reported to produce the …

The neonate has an increased susceptibility to infection, in part owing to an inability to produce
antibody to thymus-independent antigens such as bacterial polysaccharides (PS). This …

OBJECTIVES: Determine the incidence of apnea in preterm and term infants after deep
sedation (DS) compared with general anesthesia (GA). METHODS: A retrospective chart review …

CpG oligodeoxynucleotides (ODNs) stimulate adult B cells leading to cellular proliferation
and immunoglobulin production. It is unknown if CpG-ODNs similarly stimulate neonatal …

Children require painful procedures for diagnostic and therapeutic needs. Pharmacologic
and non-pharmacologic measures are needed to manage pain in order to prevent long-term …

Introduction: Defects in leukocyte localization at sites of infection have been hypothesized to
contribute to the neonates' susceptibility to infection. Adult PMNs (A-PMNs) use L-selectin …

This book provides a comprehensive overview on sedation and analgesia for the pediatric
intensivist. Divided into two primary sections, the text presents a framework on how to care for …

In the past two decades, pediatric critical care medicine (PCCM) physicians have been at the
forefront of providing care to critically ill infants and children not just within the walls of the …

In Response: In response to the issues about our study raised by Hassani and Kessell, 1 our
study included lean as well as obese patients. 2 We agree that a limitation of our study was …