Background & Aims: Liver transplantation is the primary treatment for various end-stage
hepatic diseases but is hindered by the lack of donor organs and by complications associated …

Background The role of tumor necrosis factor-α (TNF-α) and transforming growth factor-β1 (TGF-β1)
in chronic obstructive pulmonary disease (COPD) is controversial. The purpose of …

purpose. Exogenous thymosin β-4 (Tβ 4) has been shown to inhibit the apoptosis in nontransformed
human corneal epithelial cells that is triggered by ethanol. The purpose of this study …

BACKGROUND: The role of transforming growth factor β1 (TGF-β1) and tumor necrosis
factor α (TNF-α) in asthma is unclear. The aim of this study was to assess the relationships …

Apocynin suppresses the generation of reactive oxygen species (ROS) that are implicated
in ischemia-reperfusion (I/R) lung injury. We thus hypothesized that apocynin attenuates I/R. …

BACKGROUND: The mechanism between ventilator-induced lung injury (VILI) and multiple
organ injury is unclear. The aim of our study was to investigate the mechanisms of VILI-…

Rationale Apocynin suppresses the generation of reactive oxygen species (ROS) that are
implicated in ventilator-induced lung injury (VILI). We thus hypothesized that apocynin …

N-acetylcysteine (NAC) suppresses the generation of reactive oxygen species (ROS) that
are implicated in ventilator-induced lung injury (VILI). We thus hypothesised that NAC …

High tidal volume (VT) ventilation causes the release of various mediators and results in
ventilator-induced lung injury (VILI). SN50, a cell-permeable nuclear factor-κB (NF-κB) inhibitory …

NF-κB cell permeable inhibitory peptide (SN50) inhibits translocation of nuclear factor-κB (NF-κB)
and production of inflammatory cytokines that are implicated in lipopolysaccharide (…