Intranasal administration is a non-invasive route for drug delivery, which is widely used for
the local treatment of rhinitis or nasal polyposis. Since drugs can be absorbed into the …

Background Severe diaphragmatic dysfunction can prolong mechanical ventilation after
cardiac surgery. An ultrasonographic criterion for diagnosing severe diaphragmatic dysfunction …

To assess energy balance in very sick medical patients requiring prolonged acute mechanical
ventilation and its possible impact on outcome, we conducted an observational study of …

Background Usual equations for predicting resting energy expenditure (REE) are not
appropriate for critically ill patients, and indirect calorimetry criteria render its routine use difficult. …

Objective Because acute renal failure (ARF) is frequent in septic shock, an early marker of
ARF could impact on management of such patients. High renal arterial resistive index (RI) is …

Purpose The optimal treatment duration for ventilator-associated pneumonia is based on one
study dealing with late-onset of the condition. Shortening the length of antibiotic treatment …

Second-generation histamine H 1 receptor antagonists were developed to provide efficacious
treatment of allergic rhinitis (AR) and chronic idiopathic urticaria (CIU) while decreasing …

Background Morbidity and mortality conferences are a tool for evaluating care management,
but they lack a precise format for practice in intensive care units. Objectives To evaluate the …

Objective To compare the rates of clinically significant gastrointestinal bleeding and the
number of blood units and endoscopies required for gastrointestinal hemorrhage between …

Background Bitter-taste receptors (TAS2Rs) have recently been involved in the relaxation of
mouse and guinea pig airways, and increased expression of TAS2Rs was shown in blood …