Background The COPD Assessment Test (CAT) is responsive to change in patients with
chronic obstructive pulmonary disease (COPD). However, the minimum clinically important …

Background Age-related loss of muscle, sarcopenia, is recognised as a clinical syndrome
with multiple contributing factors. International European Working Group on Sarcopenia in …

Background Moving from sitting to standing is a common activity of daily living. The five-repetition
sit-to-stand test (5STS) is a test of lower limb function that measures the fastest time …

Background Frailty is an important clinical syndrome that is consistently associated with
adverse outcomes in older people. The relevance of frailty to chronic respiratory disease and its …

Background The EQ-5D, a generic health status questionnaire that is widely used in health
economic evaluation, was recently expanded to the EQ-5D-5L to address criticisms of …

In community-dwelling older adults, usual gait speed over 4 m (4MGS) consistently predicts
greater risk of adverse health outcomes. The aims of the present study were to assess the …

Background Skeletal muscle dysfunction and exercise intolerance are common in severe
chronic obstructive pulmonary disease (COPD). We assessed the effectiveness of …

Background The Clinical COPD Questionnaire (CCQ) is a simple 10-item, health-related
quality of life questionnaire (HRQoL) with good psychometric properties. However, little data …

… Claire M. Nolan … Baseline characteristics were as follows: 66 men (67%); age [mean (SD)],
55 (12) years; body mass index, 33.8 (7.5) kg/m 2 ; neck circumference, 43 (12) cm; ESS …

Usual gait speed is a consistent predictor of adverse outcomes in community-dwelling
elderly people. The reliability and validity of the 4-m gait speed (4MGS) has recently been …