Nanoparticles for intracellular-targeted drug delivery
CSO Paulo, RP das Neves, LS Ferreira - Nanotechnology, 2011 - iopscience.iop.org
Nanoparticles (NPs) are very promising for the intracellular delivery of anticancer and
immunomodulatory drugs, stem cell differentiation biomolecules and cell activity modulators. …
immunomodulatory drugs, stem cell differentiation biomolecules and cell activity modulators. …
Antifungal nanoparticles and surfaces
CSO Paulo, M Vidal, LS Ferreira - Biomacromolecules, 2010 - ACS Publications
Nosocomial fungal infections, an increasing healthcare concern worldwide, are often associated
with medical devices. We have developed antifungal nanoparticle conjugates that can …
with medical devices. We have developed antifungal nanoparticle conjugates that can …
B‐type natriuretic peptide is related to cardiac function and prognosis in hospitalized patients with decompensated cirrhosis
J Pimenta, C Paulo, A Gomes, S Silva… - Liver …, 2010 - Wiley Online Library
Background: B‐type natriuretic peptide (BNP) concentrations are high in cirrhosis, possibly
related to volume status and cirrhotic cardiomyopathy. The prognostic significance of BNP in …
related to volume status and cirrhotic cardiomyopathy. The prognostic significance of BNP in …
High antimicrobial activity and low human cell cytotoxicity of core–shell magnetic nanoparticles functionalized with an antimicrobial peptide
…, M Evangelista, RMS Cardoso, C Paulo… - … Applied Materials & …, 2016 - ACS Publications
Superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with antimicrobial
agents are promising infection-targeted therapeutic platforms when coupled with external …
agents are promising infection-targeted therapeutic platforms when coupled with external …
[HTML][HTML] Incidence of hypertension in a prospective cohort study of adults from Porto, Portugal
Background During the past 30 years, Portugal has been described as one of the countries
with highest median blood pressure levels in Europe, but the incidence of hypertension is …
with highest median blood pressure levels in Europe, but the incidence of hypertension is …
A polymeric nanoparticle formulation for targeted mRNA delivery to fibroblasts
AF Rodrigues, C Rebelo, S Simões, C Paulo… - Advanced …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer enhanced control over the production of
therapeutic proteins for many diseases. Their clinical implementation warrants formulations …
therapeutic proteins for many diseases. Their clinical implementation warrants formulations …
Leucobacter luti sp. nov., and Leucobacter alluvii sp. nov., two new species of the genus Leucobacter isolated under chromium stress
PV Morais, C Paulo, R Francisco, R Branco… - Systematic and applied …, 2006 - Elsevier
Two strains designated RF6 T and RB10 T were isolated, from activated sludge and from
river sediments, respectively, both systems receiving chromium contaminated water. …
river sediments, respectively, both systems receiving chromium contaminated water. …
Higher C‐reactive protein predicts worse prognosis in acute heart failure only in noninfected patients
P Lourenço, J Paulo Araújo, C Paulo… - Clinical …, 2010 - Wiley Online Library
Background: The prognostic role of C‐reactive protein (CRP) in acute heart failure (HF) is not
fully understood, and the impact of an infectious process in its risk‐stratification power was …
fully understood, and the impact of an infectious process in its risk‐stratification power was …
Statin-induced low cholesterol is not associated with poor outcome in chronic heart failure
S Silva, P Lourenço, C Paulo… - Journal of …, 2012 - journals.sagepub.com
Background: Low cholesterol levels are associated with a worse outcome in patients with
heart failure (HF). Use of statins in HF remains controversial. We aimed to assess whether the …
heart failure (HF). Use of statins in HF remains controversial. We aimed to assess whether the …
Antifungal activity of dental resins containing amphotericin B-conjugated nanoparticles
Objectives To evaluate the antifungal activity, biocompatibility and mechanical properties of
dental resins containing silica nanoparticles functionalized with amphotericin B (SNP-…
dental resins containing silica nanoparticles functionalized with amphotericin B (SNP-…