Tumors of the mediastinum represent a wide diversity of disease states. The location and
composition of a mass is critical to narrowing the differential diagnosis. The most common …

Interventional pulmonology is a new field within pulmonary medicine focused on the use of
advanced bronchoscopic and pleuroscopic techniques for the treatment of a spectrum of …

Malignant mesothelioma is an insidious neoplasm arising from the mesothelial surfaces of
the pleural and peritoneal cavities, the pericardium, or the tunica vaginalis. A total of 80% of …

Microaspiration is a common phenomenon in healthy subjects, but its frequency is
increased in chronic inflammatory airway diseases, and its role in inflammatory and immune …

Background: This Guideline, a collaborative effort from the American Thoracic Society,
Society of Thoracic Surgeons, and Society of Thoracic Radiology, aims to provide evidence-…

Background Bronchial thermoplasty (BT) has previously been shown to improve asthma
control out to 2 years in patients with severe persistent asthma. Objective We sought to assess …

Purpose: Listeria monocytogenes (Lm)-based vaccines stimulate both innate and adaptive
immunity. ANZ-100 is a live-attenuated Lm strain (Lm ΔactA/ΔinlB). Uptake by phagocytes in …

Multiple lines of investigation have shown that the gut microbiota affects host immune
response to immunotherapy in cancer. Here, we support that the local airway microbiota …

Malignant pleural mesothelioma is a fatal neoplasm that is unresponsive to standard modalities
of cancer therapy. We conducted a phase I dose-escalation clinical trial of adenoviral (Ad…

Rationale: In lung cancer, upregulation of the PI3K (phosphoinositide 3-kinase) pathway is
an early event that contributes to cell proliferation, survival, and tissue invasion. Upregulation …