The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

… Grieco has received payments for travel expenses by Maquet, Getinge and Air Liquide.
Mas… Grieco and Massimo Antonelli disclose a research grant by General Electrics Healthcare. …

Patient self-inflicted lung injury and positive end-expirato... : Current Opinion in Critical Care
Patient self-inflicted lung injury and positive end-expiratory pressure for safe spontaneous …

Background Patients with COVID-19 can develop acute respiratory distress syndrome (ARDS),
which is associated with high mortality. The aim of this study was to examine the …

… We read with interest the study by Grieco and coworkers which appeared in JAMA (1).
This was the first head-to-head comparison of helmet noninvasive ventilation (NIV) and high-flow …

Background Limited data are available on the use of prone position in intubated, invasively
ventilated patients with Coronavirus disease-19 (COVID-19). Aim of this study is to …

Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is
associated with poor clinical outcomes. Although the importance and impact of lung-protective …

Background Whether respiratory physiology of COVID-19-induced respiratory failure is
different from acute respiratory distress syndrome (ARDS) of other etiologies is unclear. We …

Rationale: Response to positive end-expiratory pressure (PEEP) in acute respiratory
distress syndrome depends on recruitability. We propose a bedside approach to estimate …

Rationale: Esophageal manometry is the clinically available method to estimate pleural
pressure, thus enabling calculation of transpulmonary pressure (Pl). However, many concerns …