Helper T (Th) cell differentiation is highly regulated by cytokines but initiated by mitogens.
By examining gene expression in discrete generations of dividing cells, we have delineated …

To determine whether DNA immunization could elicit protective immunity to Leishmania major
in susceptible BALB/c mice, cDNA for the cloned Leishmania antigen LACK was inserted …

Background Respiratory failure is a leading cause of postoperative morbidity and mortality
in patients undergoing pneumonectomy. The authors hypothesized that intraoperative …

Objective To determine the frequency and spectrum of myocardial dysfunction in patients with
severe sepsis and septic shock using transthoracic echocardiography and to evaluate the …

Background: While acute lung injury (ALI) is among the most serious postoperative pulmonary
complications, its incidence, risk factors and outcome have not been prospectively studied…

Objective: To summarize published data regarding the steps of rapid-sequence intubation (RSI);
review premedications, induction agents, neuromuscular blockers (NMB), and studies …

Natural transformation is a dominant force in bacterial evolution by promoting horizontal
gene transfer. This process may have devastating consequences, such as the spread of …

Assimilation of nitrogen is an essential process in bacteria. The nitrogen regulation stress
response is an adaptive mechanism used by nitrogen-starved Escherichia coli to scavenge for …

Sea turtle fibropapillomatosis (FP) is a disease marked by proliferation of benign but debilitating
cutaneous fibropapillomas and occasional visceral fibromas. Transmission experiments …

Follicular helper T cells (Tfh cells) are the major producers of interleukin-4 (IL-4) in secondary
lymphoid organs where humoral immune responses develop. Il4 regulation in Tfh cells …