User profiles for E. L. Morgan

Ethan L Morgan

Lecturer in Biochemistry and Biomedicine, School of Life Sciences, University of Sussex
Verified email at sussex.ac.uk
Cited by 828

[HTML][HTML] The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

…, MR Patterson, EL Morgan… - Journal of General …, 2021 - microbiologyresearch.org
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99 % of cervical cancer cases, and a significant proportion of oropharyngeal and …

[HTML][HTML] Manipulation of JAK/STAT signalling by high-risk HPVs: Potential therapeutic targets for HPV-associated malignancies

EL Morgan, A Macdonald - Viruses, 2020 - mdpi.com
Human papillomaviruses (HPVs) are small, DNA viruses that cause around 5% of all
cancers in humans, including almost all cervical cancer cases and a significant proportion of …

[HTML][HTML] Regulation of NFκB signalling by ubiquitination: a potential therapeutic target in head and neck squamous cell carcinoma?

EL Morgan, Z Chen, C Van Waes - Cancers, 2020 - mdpi.com
Simple Summary Head and neck cancer is the sixth most common cancer worldwide and
typically caused by smoking and alcohol consumption, or infection with Human Papillomavirus …

Trabecular bone mineral density in idiopathic scoliosis

SD Cook, AF Harding, EL Morgan… - Journal of Pediatric …, 1987 - journals.lww.com
The association of idiopathic scoliosis with an osteoporotic state has been indicated previously.
The present study compared the trabecular bone mineral densities of 44 adolescent …

[HTML][HTML] Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis

EL Morgan, A Macdonald - PLoS pathogens, 2019 - journals.plos.org
Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer.
Although the fundamental link between HPV infection and oncogenesis is established, the …

[HTML][HTML] E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer

EL Morgan, JA Scarth, MR Patterson… - Cell Death & …, 2021 - nature.com
Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing to
~5% of all human cancers including almost all cases of cervical cancer and a growing …

[HTML][HTML] Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC)

EL Morgan, T Toni, R Viswanathan, Y Robbins… - Cell Death & …, 2023 - nature.com
… For UPCI:SCC090 tumor xenografts, mice were randomised into 2 groups: vehicle control
(Cremophor EL and polyethylene glycol 400 (1:1) 0.9% saline) or b-AP15 (5 mg/kg). Mouse …

Stress and glucocorticoid inhibit apical GLUT2‐trafficking and intestinal glucose absorption in rat small intestine

…, PA Helliwell, OJ Mace, EL Morgan… - The Journal of …, 2004 - Wiley Online Library
We have proposed a new model of rat intestinal sugar absorption in which high glucose
concentrations promote rapid insertion of GLUT2 into the apical membrane, so that absorptive …

C5a-mediated release of interleukin 6 by human monocytes

…, M Smith, DJ Noonan, TE Hugli, EL Morgan - Clinical immunology and …, 1990 - Elsevier
Recombinant human C5a (rC5a) was assessed for its ability to induce interleukin 6 (IL-6)
production in human peripheral blood-derived mononuclear cell (PBMC) cultures. rC5a was …

[PDF][PDF] New structural insights into the genome and minor capsid proteins of BK polyomavirus using cryo-electron microscopy

DL Hurdiss, EL Morgan, RF Thompson, EL Prescott… - Structure, 2016 - cell.com
BK polyomavirus is the causative agent of several diseases in transplant patients and the
immunosuppressed. In order to better understand the structure and life cycle of BK, we …