… F-actin 85,86 that are restored to normal within 3 h by a single injection of either T 4 or rT 3
(Ref. 86). Importantly, T 3 has little, if any, effect on F-actin content either in vivo or in vitro 86 . …

The processes and pathways mediating the intermediary metabolism of carbohydrates,
lipids, and proteins are all affected by thyroid hormones (THs) in almost all tissues. Particular …

Thyroid hormones exert profound effects on the energy metabolism. An inspection of the
early and more recent literature shows that several targets at the cellular level have been …

… Goglia, F., Skulachev, VP A function for novel uncoupling proteins: antioxidant defense of
mitochondrial matrix by translocating fatty acid peroxides from the inner to the outer membrane …

The overall effect of brain zinc (Zn 2+) in the progression and development of Alzheimer's
disease (AD) is still not completely understood. Although an excess of Zn 2+ can exacerbate …

The short‐term effects of thyroid hormones, which do not occur via gene expression, were
postulated to be based on interaction of diiodothyronines with mitochondria. We demonstrate …

Thyroid hormone (TH/T3) exerts many of its effects on energy metabolism by affecting gene
transcription. However, although this is an important target for T3, only a limited number of T3…

Distinct brain peptidergic circuits govern peripheral energy homeostasis and related behavior.
Here we report that mitochondrial uncoupling protein 2 (UCP2) is expressed discretely in …

Fibrates are hypolipidemic drugs that activate the peroxisome proliferator-activated receptors.
Since fibrates may also increase energy expenditure, we investigated whether fenofibrate (…

… Cioffi F, Senese R, Lanni A & Goglia F 2013 Thyroid hormones and mitochondria: with a
brief look at derivatives and analogues. Molecular and Cellular Endocrinology 379 51–61. (doi:…