Objective To determine the prevalence of patient–ventilator asynchrony in patients receiving
non-invasive ventilation (NIV) for acute respiratory failure. Design Prospective multicenter …

Objective: To compare the physiologic effects of noninvasive pressure-support ventilation (NPSV)
delivered by a facemask, a helmet with the same settings, and a helmet with specific …

Introduction We hypothesized that the use of intrapulmonary percussive ventilation (IPV), a
technique designed to improve mucus clearance, could prove effective in avoiding further …

Background Avoiding intubation is a major goal in the management of respiratory failure,
particularly in immunosuppressed patients. Nevertheless, there are only limited data on the …

Background Chronic obstructive pulmonary disease (COPD) is characterized by peribronchial
fibrosis. The chronic course of COPD is worsened by recurrent acute exacerbations. …

… Frédéric Vargas MD, PhD e , Bruno Filloux MD e , David Vandroux MD f , Julien Jabot MD f
, Bruno François MD a b , Nicolas Pichon MD a b , Marc Clavel MD a b , Bruno Levy MD, PhD …

To test the hypothesis that a new program of antibiotic strategy control can minimize the
incidence of ventilator-associated pneumonia (VAP) caused by potentially antibiotic-resistant …

Introduction The purpose of this study was to investigate the relationship among Pseudomonas
aeruginosa acquisition on the intensive care unit (ICU), environmental contamination …

Purpose Ultrasonography allows the direct observation of the diaphragm. Its thickness
variation measured in the zone of apposition has been previously used to diagnose diaphragm …

Aminoglycoside nephrotoxicity has been reported in patients with sepsis, and several risk
factors have been described. Once-daily dosing and shorter treatment have reduced …