In humans, several grams of IgA are secreted every day in the intestinal lumen. While only
one IgA isotype exists in mice, humans secrete IgA1 and IgA2, whose respective relations …

Rationale: In the critically ill patients, lung ultrasound (LUS) is increasingly being used at
the bedside for assessing alveolar-interstitial syndrome, lung consolidation, pneumonia, …

Objective: Postextubation distress after a successful spontaneous breathing trial is associated
with increased morbidity and mortality. Predicting postextubation distress is therefore a …

Methods Prospective observational cohort study. All critically ill patients intubated with a
high-volume low-pressure endotracheal tube were eligible. After manual adjustment of cuff …

Introduction The aim of this study was to determine incidence, risk factors, and impact on
outcome of intensive care unit (ICU)-acquired Stenotrophomonas maltophilia. Methods This …

Introduction The study was designed to assess the impact of fluid loading on lung aeration,
oxygenation and hemodynamics in patients with septic shock and acute respiratory distress …

The aim of this review is to perform a critical analysis of experimental studies on aerosolized
antibiotics and draw lessons for clinical use in patients with ventilator-associated pneumonia…

Background Lung ultrasound is increasingly used in critically ill patients as an alternative to
bedside chest radiography, but the best training method remains uncertain. This study …

Objective: To determine the relationship between immunosuppression and intensive care
unit (ICU)-acquired multidrug-resistant (MDR) bacteria. Design: Retrospective case-control …

Only limited data exist on Pseudomonas aeruginosa ventilator-associated pneumonia (VAP)
treated with imipenem, meropenem, or doripenem. Therefore, we conducted a prospective …