Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by recurrent infections
of the upper and lower respiratory tract, reduced fertility in males and situs inversus in …

Reduced generation of multiple motile cilia (RGMC) is a rare mucociliary clearance disorder.
Affected persons suffer from recurrent infections of upper and lower airways because of …

Defects of motile cilia cause primary ciliary dyskinesia (PCD), characterized by recurrent
respiratory infections and male infertility. Using whole-exome resequencing and high-…

In recent years and particularly in the last 5 years, there have been substantial advances in
our understanding of the mechanisms governing mucus clearance (MC) in health and …

Background Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by impaired
ciliary function, leading to chronic sinopulmonary disease. The genetic causes of PCD are …

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous recessive disorder caused
by several distinct defects in genes responsible for ciliary beating, leading to defective …

Primary ciliary dyskinesia (PCD) is a recessively inherited disease that leads to chronic
respiratory disorders owing to impaired mucociliary clearance. Conventional transmission …

Assessment of changes in airway dimensions during bronchoconstriction is conventionally
based on measurements of respiratory mechanics. We evaluated the efficacy of ultrafast high-…

Despite recent progress in defining the ciliome, the genetic basis for many cases of primary
ciliary dyskinesia (PCD) remains elusive. We evaluated five children from two unrelated, …

Objective. Masks are an essential interface between valved holding chambers (VHCs), or
spacers, and a small child's face for providing aerosol therapy. Clinical experience suggests …