Oxygen radical mechanisms of brain injury following ischemia and reperfusion

RJ Traystman, JR Kirsch… - Journal of Applied …, 1991 - journals.physiology.org
This review addresses current understanding of oxygen radical mechanisms as they relate
to the brain during ischemia and reperfusion. The mechanism for radical production remains …

[HTML][HTML] Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis

LJ Martin, NA Al-Abdulla, AM Brambrink, JR Kirsch… - Brain research …, 1998 - Elsevier
In the human brain and spinal cord, neurons degenerate after acute insults (eg, stroke,
cardiac arrest, trauma) and during progressive, adult-onset diseases [eg, amyotrophic lateral …

Effects of anesthesia on cerebral blood flow, metabolism, and neuroprotection

AM Slupe, JR Kirsch - Journal of Cerebral Blood Flow & …, 2018 - journals.sagepub.com
Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

Inhalational anesthetics as neuroprotectants or chemical preconditioning agents in ischemic brain

H Kitano, JR Kirsch, PD Hurn… - Journal of Cerebral …, 2007 - journals.sagepub.com
This review will focus on inhalational anesthetic neuroprotection during cerebral ischemia
and inhalational anesthetic preconditioning before ischemic brain injury. The limitations and …

Critical care and perioperative management in traumatic spinal cord injury

RD Stevens, A Bhardwaj, JR Kirsch… - Journal of …, 2003 - journals.lww.com
Traumatic spinal cord injury is frequently associated with brain injury and with alterations in
respiratory and cardiovascular function that require critical care management. Complications …

Local anesthetic Schwann cell toxicity is time and concentration dependent

…, PD Hurn, MR Grafe, JR Kirsch - Regional Anesthesia & …, 2011 - rapm.bmj.com
Background: Peripheral nerve blocks with local anesthetics (LAs) are commonly performed
to provide surgical anesthesia or postoperative analgesia. Nerve injury resulting in persistent …

Effects of playing violent versus nonviolent video games on the aggressive ideation of aggressive and nonaggressive children.

D Graybill, JR Kirsch, ED Esselman - Child Study Journal, 1985 - psycnet.apa.org
39 2nd, 38 4th, and 39 6th graders were identified as aggressive or nonaggressive on the
basis of peer ratings. Ss then played a violent or nonviolent video game for 8 min and were …

The effect of needle gauge and lidocaine pH on pain during intradermal injection

SC Palmon, AT Lloyd, JR Kirsch - Anesthesia & Analgesia, 1998 - journals.lww.com
Local anesthetics can produce pain during skin infiltration. We designed a randomized,
prospective trial to determine whether needle gauge and/or solution pH affect pain during the …

The effect of the prone position on pulmonary mechanics is frame-dependent

SC Palmon, JR Kirsch, JA Depper… - Anesthesia & …, 1998 - journals.lww.com
By compressing the abdomen and restricting chest wall movement, the prone position
compromises pulmonary compliance. For spine surgery, placing the anesthetized patient into the …

Postischemic cerebral blood flow recovery in the female: effect of 17β-estradiol

…, MT Littleton-Kearney, JR Kirsch… - Journal of Cerebral …, 1995 - journals.sagepub.com
Female reproductive hormones are considered to be protective agents in atherosclerotic
vascular disease and stroke. The present study determined if there are unique cerebrovascular …