Obstructive sleep apnea syndrome in children is a manifestation of sleep-disordered breathing
and associated with a number of complications. Structural narrowing of the upper airway …

… 12 De Backer JW, Vos WG, Verhulst SL, De Backer W. Novel imaging techniques using
computer methods for the evaluation of the upper airway in patients with sleep-disordered …

… Figure printed with permission from De Backer et al. … De Backer are the directors/founders
of FluidDA nv, a company providing services in the healthcare industry, that is responsible for …

Mandibular advancement devices (MADs) have emerged as a popular alternative for the
treatment of sleep-disordered breathing. These devices bring the mandibula forward in order to …

Computational fluid dynamics (CFD) is increasingly applied in the respiratory domain. The
ability to simulate the flow through a bifurcating tubular system has increased the insight into …

The effect of a bronchodilator in asthmatics is only partially described by changes in
spirometric values since no information on regional differences can be obtained. Imaging …

… de Backer and Wim G. Vos are shareholders of FluidDA NV, a company that … de Backer
and Wim G. Vos are shareholders of FluidDA NV, a company that commercializes some of the …

Background: As the upper airway is the most important limiting factor for the deposition of
inhalation medication in the lower airways, it is interesting to assess how its morphology varies …

Background Salbutamol and ipratropium bromide improve lung function in patients with chronic
obstructive pulmonary disease (COPD). However, their bronchodilating effect has not yet …

… These models comprise of accurate geometrical representations of the airway structures
and realistic boundary conditions which drive the flow (De Backer et al., 2007b). The CFD …