Background More than 20% of hospitalized patients with COVID-19 demonstrate ARDS
requiring ICU admission. The long-term respiratory sequelae in such patients remain unclear. …

Rationale: Inflammation and oxidative stress contribute to muscle dysfunction in patients
with chronic obstructive pulmonary disease (COPD). Oxidants contained in cigarette smoke (CS…

The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the metabolic
pathways that are altered early with viral infection and their association with disease …

Background: Although exercise training has beneficial effects on skeletal muscle bioenergetics
and exercise performance in patients with severe chronic obstructive pulmonary disease (…

In the diaphragms of chronic obstructive pulmonary disease (COPD) patients, the nature of
oxidatively modified proteins and superoxide anion production were explored. Diaphragm …

Discrepancies exist regarding the involvement of cellular inflammation and apoptosis in the
muscle dysfunction of chronic obstructive pulmonary disease (COPD) patients with …

Purpose Although the prevalence of community-acquired respiratory bacterial coinfection
upon hospital admission in patients with coronavirus disease 2019 (COVID-19) has been …

BACKGROUND: Despite wide use of noninvasive ventilation (NIV) in several clinical settings,
the beneficial effects of NIV in patients with hypoxemic acute respiratory failure (ARF) due …

Background Influenza A (H1N1)pdm09 virus infection acquired in the hospital and in critically
ill patients admitted to the intensive care unit (ICU) has been poorly characterized. Aim To …

Purpose Although there is evidence supporting the benefits of corticosteroids in patients
affected with severe coronavirus disease 2019 (COVID-19), there is little information related to …