User profiles for J. Pepin

Jacques Pepin

Universite de Sherbrooke
Verified email at usherbrooke.ca
Cited by 23598

[HTML][HTML] Risk Factors for Recurrence, Complications and Mortality in Clostridium difficile Infection: A Systematic Review

CN Abou Chakra, J Pepin, S Sirard, L Valiquette - PloS one, 2014 - journals.plos.org
Background Clostridium difficile infection (CDI) can lead to complications, recurrence, and
death. Numerous studies have assessed risk factors for these unfavourable outcomes, but …

Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis

…, CM Nunez, SR Patel, T Penzel, JL Pépin… - The Lancet …, 2019 - thelancet.com
Background There is a scarcity of published data on the global prevalence of obstructive
sleep apnoea, a disorder associated with major neurocognitive and cardiovascular sequelae. …

Human African trypanosomiasis: an emerging public health crisis

DH Smith, J Pepin, AHR Stich - British medical bulletin, 1998 - academic.oup.com
There is a dramatic resurgence of human African trypanosomiasis (HAT) in sub-Saharan
Africa. Tb gambiense is spreading epidemically in large areas of Central Africa, especially the …

Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious …

…, CP Kelly, VG Loo, LC McDonald, J Pepin… - Infection Control & …, 2010 - cambridge.org
Since publication of the Society for Healthcare Epidemiology of America position paper on
Clostridium difficile infection in 1995, significant changes have occurred in the epidemiology …

Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe

…, J Pepin, A Fang, G Killgore, A Thompson, J Brazier… - The Lancet, 2005 - thelancet.com
Background Toxins A and B are the primary virulence factors of Clostridium difficile. Since
2002, an epidemic of C difficile-associated disease with increased morbidity and mortality has …

Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity

J Pépin, L Valiquette, ME Alary, P Villemure, A Pelletier… - Cmaj, 2004 - Can Med Assoc
Background: Recent reports suggest that Clostridium difficile colitis may be evolving into a
more severe disease. During the second half of 2002 we noted an increase in the number of …

Emergence of Fluoroquinolones as the Predominant Risk Factor for Clostridium difficile–Associated Diarrhea: A Cohort Study during an Epidemic in Quebec

J Pépin, N Saheb, MA Coulombe… - Clinical Infectious …, 2005 - academic.oup.com
Background . Since 2002, an epidemic of Clostridium difficile–associated-diarrhea (CDAD)
associated with a high case-fatality rate has involved >30 hospitals in the province of Quebec…

The early spread and epidemic ignition of HIV-1 in human populations

…, AJ Tatem, JD Sousa, N Arinaminpathy, J Pépin… - science, 2014 - science.org
Thirty years after the discovery of HIV-1, the early transmission, dissemination, and establishment
of the virus in human populations remain unclear. Using statistical approaches applied …

Mortality attributable to nosocomial Clostridium difficile–associated disease during an epidemic caused by a hypervirulent strain in Quebec

J Pépin, L Valiquette, B Cossette - Cmaj, 2005 - Can Med Assoc
Background: Since 2002 an epidemic of Clostridium difficile–associated disease (CDAD)
caused by a hypervirulent toxinotype III ribotype 027 strain has spread to many hospitals in …

Increasing Risk of Relapse after Treatment of Clostridium difficile Colitis in Quebec, Canada

J Pépin, ME Alary, L Valiquette, E Raiche… - Clinical Infectious …, 2005 - academic.oup.com
Background Clinicians who treat patients with Clostridium difficile–associated diarrhea (CDAD)
in Quebec, Canada, have noted an apparent increase in the proportion of patients who …