International conference for the development of consensus on the diagnosis and treatment of ventilator-associated pneumonia

J Rello, JA Paiva, J Baraibar, F Barcenilla, M Bodi… - Chest, 2001 - Elsevier
Ventilator-associated pneumonia (VAP) is an important health problem that still generates
great controversy. A consensus conference attended by 12 researchers from Europe and …

Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths

…, T Le Voyer, J Rosain, Q Philippot, J Manry… - Science …, 2021 - science.org
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

J Manry, P Bastard, A Gervais… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …

[HTML][HTML] Mortality comparison between the first and second/third waves among 3,795 critical COVID-19 patients with pneumonia admitted to the ICU: A multicentre …

…, J Solé-Violán, E Díaz, J Gómez… - The Lancet Regional …, 2021 - thelancet.com
Background It is unclear whether the changes in critical care throughout the pandemic have
improved the outcomes in coronavirus disease 2019 (COVID-19) patients admitted to the …

Antibiotic prescription for community-acquired pneumonia in the intensive care unit: impact of adherence to Infectious Diseases Society of America guidelines on …

…, J Garnacho, J Blanquer, J Jimenez… - Clinical Infectious …, 2005 - academic.oup.com
Background . The purpose of our study was to analyze prognostic factors associated with
mortality for patients with severe community-acquired pneumonia (CAP). Methods . We …

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

…, T Le Voyer, L Bizien, J Manry, J Rosain… - Journal of Experimental …, 2022 - rupress.org
Autoantibodies neutralizing type I interferons (IFNs) can underlie critical COVID-19
pneumonia and yellow fever vaccine disease. We report here on 13 patients harboring …

Implications of COPD in patients admitted to the intensive care unit by community-acquired pneumonia

…, A Torres, J Roig, J Sole-Violan… - European …, 2006 - Eur Respiratory Soc
The mortality rate of chronic obstructive pulmonary disease (COPD) patients with community-acquired
pneumonia (CAP) is reported to be low. However, studies carried out to date have …

Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock

…, J Solé-Violán, J Rello… - Critical care …, 2007 - journals.lww.com
Objective: To assess whether combination antibiotic therapy improves outcome of severe
community-acquired pneumonia in the subset of patients with shock. Design: Secondary …

[HTML][HTML] Increased incidence of co-infection in critically ill patients with influenza

…, F Alvarez-Lerma, LD Bos, J Solé-Violán… - Intensive care …, 2017 - Springer
Background Co-infection is frequently seen in critically ill patients with influenza, although
the exact rate is unknown. We determined the rate of co-infection, the risk factors and the …

HLA genetic polymorphisms and prognosis of patients with COVID-19

…, A Franco, Y Barrios, JJ Cáceres, J Solé-Violán… - Medicina intensiva, 2021 - Elsevier
Objective Different genetic polymorphisms of human leukocyte antigen (HLA) have been
associated with the risk and prognosis of autoimmune and infectious diseases. The objectives …