Mice with homologous disruption of the gene coding for either the p35 subunit or the p40
subunit of interleukin‐12 (IL‐12) and derived from a strain genetically resistant to infection with …

Conserved molecular patterns derived from pathogenic microorganisms prime antigen-presenting
dendritic cells (DC) to induce adaptive T cell responses. In contrast, virus-infected or …

BACKGROUND: Sleeve lobectomy (SL) in a lung-saving procedure indicated for central
tumors for which the alternative is pneumonectomy (PN). Although it has been suggested that it …

Maturity-onset diabetes of the young (MODY) 5 is caused by mutations in the TCF2 gene
encoding the transcription factor hepatocyte nuclear factor-1β. However, in 60% of the patients …

Immunity to infection with intracellular pathogens is regulated by interleukin 12 (IL-12), which
mediates protective T helper type 1 (T H 1) responses, or IL-4, which induces T H 2 cells …

BALB/c mice develop aberrant T helper 2 (Th2) responses and suffer progressive disease
after infection with Leishmania major. These outcomes depend on the production of interleukin…

: One hundred fifty-one patients with colorectal polyps containing invasive adenocarcinoma
treated by resection were studied to determine the incidence of lymph node metastasis and …

The pathogenic importance of L3T4+ T cells in the development of murine cerebral malaria
was demonstrated by the following observations. First, in vivo administration of an anti-L3T4 …

Mice with homologous disruption of the gene coding for the ligand-binding chain of the
interferon (IFN) gamma receptor and derived from a strain genetically resistant to infection with …

Recent evidence indicates that B cells are required for susceptibility to infection with
Leishmania major in BALB/c mice. In this study, we analyzed the role of the IL-10 produced by B …