Background The Surviving Sepsis Campaign recommends targeting a mean arterial pressure
of at least 65 mm Hg during initial resuscitation of patients with septic shock. However, …

Background Whether noninvasive ventilation should be administered in patients with acute
hypoxemic respiratory failure is debated. Therapy with high-flow oxygen through a nasal …

Rationale: Respiratory events are common in hematology and oncology patients and manifest
as hypoxemic acute respiratory failure (ARF) in up to half the cases. Identifying the cause …

Objective: To describe the clinical spectrum of infective endocarditis in critically ill patients
and assess the impact of neurologic complications on outcomes. Design: Prospective …

Background— Targeted temperature management is recommended after out-of-hospital
cardiac arrest. Whether advanced internal cooling is superior to basic external cooling remains …

Rationale: Encephalitis caused by anti–N-methyl-d-aspartate receptor (NMDAR) antibodies
is the leading cause of immune-mediated encephalitis. There are limited data on intensive …

Aims To assess long-term outcomes and the management of critical left-sided infective
endocarditis (IE) and evaluate the impact of surgery. Methods and results Among the 198 patients …

OBJECTIVE: To evaluate the clinical relevance of the weaning from mechanical ventilation
classification system derived from the 2005 international consensus conference, in patients …

Introduction The aim of the study was to determine whether the use of a nurses' protocol-directed
weaning procedure, based on the French intensive care society (SRLF) consensus …

BACKGROUND: Inhaled sedation is efficient and easily controllable; in low concentrations it
causes minimal changes in the patient and very little interference with hemodynamics. …