[HTML][HTML] High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure

JP Frat, AW Thille, A Mercat, C Girault… - … England Journal of …, 2015 - Mass Medical Soc
Background Whether noninvasive ventilation should be administered in patients with acute
hypoxemic respiratory failure is debated. Therapy with high-flow oxygen through a nasal …

[HTML][HTML] Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial

…, P Bailly, N Ferrière, AW Thille, JP Frat… - The Lancet …, 2021 - thelancet.com
Background Awake prone positioning has been reported to improve oxygenation for patients
with COVID-19 in retrospective and observational studies, but whether it improves patient-…

[HTML][HTML] Targeted temperature management for cardiac arrest with nonshockable rhythm

…, A Cariou, T Boulain, N Brule, JP Frat… - … England Journal of …, 2019 - Mass Medical Soc
Background Moderate therapeutic hypothermia is currently recommended to improve neurologic
outcomes in adults with persistent coma after resuscitated out-of-hospital cardiac arrest. …

Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a …

…, T Boulain, A Desachy, F Bellec, M Clavel, JP Frat… - Jama, 2013 - jamanetwork.com
Importance Monitoring of residual gastric volume is recommended to prevent ventilator-associated
pneumonia (VAP) in patients receiving early enteral nutrition. However, studies have …

An index combining respiratory rate and oxygenation to predict outcome of nasal high-flow therapy

…, G Hernández, M García-de-Acilu, JP Frat… - American journal of …, 2019 - atsjournals.org
Rationale: One important concern during high-flow nasal cannula (HFNC) therapy in patients
with acute hypoxemic respiratory failure is to not delay intubation. Objectives: To validate …

Intubation practices and adverse peri-intubation events in critically ill patients from 29 countries

…, R Francis, DG Franco, P Franczyk, JP Frat… - Jama, 2021 - jamanetwork.com
Importance Tracheal intubation is one of the most commonly performed and high-risk
interventions in critically ill patients. Limited information is available on adverse peri-intubation …

Non-invasive ventilation versus high-flow nasal cannula oxygen therapy with apnoeic oxygenation for preoxygenation before intubation of patients with acute …

JP Frat, JD Ricard, JP Quenot, N Pichon… - The Lancet …, 2019 - thelancet.com
Background Non-invasive ventilation has never been compared with high-flow oxygen to
determine whether it reduces the risk of severe hypoxaemia during intubation. We aimed to …

Epidemiology of weaning outcome according to a new definition. The WIND study

…, S Grange, G Barberet, PG Guitard, JP Frat… - American journal of …, 2017 - atsjournals.org
Rationale: The weaning process concerns all patients receiving mechanical ventilation. A
previous classification into simple, prolonged, and difficult weaning ignored weaning failure …

[HTML][HTML] The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline

…, A Dessap-Mekontso, J Fraser, JP Frat… - Intensive care …, 2020 - Springer
Purpose High flow nasal cannula (HFNC) is a relatively recent respiratory support technique
which delivers high flow, heated and humidified controlled concentration of oxygen via the …

High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis

…, D Granton, DX Wang, Y Helviz, S Einav, JP Frat… - Intensive care …, 2019 - Springer
Background This systematic review and meta-analysis summarizes the safety and efficacy
of high flow nasal cannula (HFNC) in patients with acute hypoxemic respiratory failure. …