[HTML][HTML] Hydrocortisone plus fludrocortisone for adults with septic shock
…, F Baudin, A Combes, J Bohé… - … England Journal of …, 2018 - Mass Medical Soc
Background Septic shock is characterized by dysregulation of the host response to infection,
with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with …
with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with …
Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose‐response study
J Bohé, A Low, RR Wolfe… - The Journal of physiology, 2003 - Wiley Online Library
To test the hypothesis that muscle protein synthesis (MPS) is regulated by the concentration
of extracellular amino acids, we investigated the dose‐response relationship between the …
of extracellular amino acids, we investigated the dose‐response relationship between the …
Rapid report: latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids
J Bohé, JFA Low, RR Wolfe… - The Journal of …, 2001 - Wiley Online Library
1 The aim of this study was to describe the time course of the response of human muscle
protein synthesis (MPS) to a square wave increase in availability of amino acids (AAs) in …
protein synthesis (MPS) to a square wave increase in availability of amino acids (AAs) in …
Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock
G Monneret, A Lepape, N Voirin, J Bohé, F Venet… - Intensive care …, 2006 - Springer
Objective The immediate overwhelming release of inflammatory mediators in septic shock is
rapidly followed by strong anti-inflammatory responses inducing a state of …
rapidly followed by strong anti-inflammatory responses inducing a state of …
[HTML][HTML] Timing of renal-replacement therapy in patients with acute kidney injury and sepsis
…, F Montini, R Bruyère, C Lebert, J Bohé… - … England Journal of …, 2018 - Mass Medical Soc
Background Acute kidney injury is the most frequent complication in patients with septic
shock and is an independent risk factor for death. Although renal-replacement therapy is the …
shock and is an independent risk factor for death. Although renal-replacement therapy is the …
Increased circulating regulatory T cells (CD4+CD25+CD127−) contribute to lymphocyte anergy in septic shock patients
…, A Geeraert, C Malcus, F Poitevin, J Bohé… - Intensive care …, 2009 - Springer
Purpose Sepsis syndrome represents the leading cause of death in intensive care unit.
Patients present features consistent with a decline in immune responsiveness potentially …
Patients present features consistent with a decline in immune responsiveness potentially …
Marked elevation of human circulating CD4+ CD25+ regulatory T cells in sepsis-induced immunoparalysis
G Monneret, AL Debard, F Venet, J Bohe… - Critical care …, 2003 - journals.lww.com
Objective Immunoparalysis has recently emerged as a possible cause explaining the failure
of clinical trials in septic shock. Because human peripheral blood CD4+ CD25+ T cells have …
of clinical trials in septic shock. Because human peripheral blood CD4+ CD25+ T cells have …
Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised …
…, A Robine, M Beuzelin, J Badie, G Chevrel, J Bohe… - The Lancet, 2021 - thelancet.com
Background Delaying renal replacement therapy (RRT) for some time in critically ill patients
with severe acute kidney injury and no severe complication is safe and allows optimisation …
with severe acute kidney injury and no severe complication is safe and allows optimisation …
The anti-inflammatory response dominates after septic shock: association of low monocyte HLA-DR expression and high interleukin-10 concentration
G Monneret, ME Finck, F Venet, AL Debard, J Bohé… - Immunology letters, 2004 - Elsevier
The diminished expression of HLA-DR on monocytes has been proposed as a reliable
marker of immunosuppression occuring during septic shock. The objective of the present …
marker of immunosuppression occuring during septic shock. The objective of the present …
Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock
…, A Lepape, N Voirin, E Tognet, F Venet, J Bohé… - Intensive care …, 2010 - Springer
Purpose Sepsis-induced immunosuppression is postulated to contribute to a heightened
risk of nosocomial infection (NI). This prospective, single-center, observational study was …
risk of nosocomial infection (NI). This prospective, single-center, observational study was …