Many types of positive airway pressure (PAP) devices are used to treat sleep-disordered
breathing including obstructive sleep apnea, central sleep apnea, and sleep-related …

Study Objectives: To describe sex, age, and body mass index (BMI) differences in comorbidities
and polysomnography measures, categorized using 3 different apnea-hypopnea index (…

Objective Apnea/hypopnea index (AHI), especially without arousal criteria, does not
adequately risk stratify patients with mild obstructive sleep apnea (OSA). We describe and test …

Patients with prolonged mechanical ventilation have a high one year mortality, with recognized
contributing factors including COPD, cardiac failure, renal failure, and respiratory muscle …

Insurance coverage policies define the diagnostic criteria and adherence requirements for
patients to qualify for initial and ongoing therapy with continuous positive airway pressure (…

To the Editor: Treatment-emergent central sleep apnea (TEC) is the development or persistence
of central sleep apneas during positive airway pressure (PAP) therapy in subjects with …

… Johnson KG 1 , Johnson DC 2 …

Mitogen-activated/extracellular response kinase kinase (MEK) kinase (MEKK) is a serine-threonine
kinase that regulates sequential protein phosphorylation pathways, leading to the …

Treatment of L929 cells with tumor necrosis factor α (TNFα) activates a programmed cell
death pathway resulting in apoptosis. We investigated the intracellular signaling pathways …

Locoregional delivery of chimeric antigen receptor (CAR) T cells has resulted in objective
responses in adults with glioblastoma, but the feasibility and tolerability of this approach is yet …