An imbalance in TAZ and YAP expression in hepatocellular carcinoma confers cancer stem cell–like behaviors contributing to disease progression
…, T Higashi, N Yokoyama, T Kaida, K Sakamoto… - Cancer research, 2015 - AACR
Transcriptional coactivator with PDZ-binding motif (TAZ) and yes-associated protein (YAP)
are equivalently placed downstream effectors of the Hippo pathway with oncogenic roles in …
are equivalently placed downstream effectors of the Hippo pathway with oncogenic roles in …
Enhancer of zeste homolog 2 (EZH2) promotes progression of cholangiocarcinoma cells by regulating cell cycle and apoptosis
S Nakagawa, H Okabe, Y Sakamoto, H Hayashi… - Annals of surgical …, 2013 - Springer
Background Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb
repressive complex 2 (PRC2). When present in PRC2, EZH2 catalyzes trimethylation on lysine …
repressive complex 2 (PRC2). When present in PRC2, EZH2 catalyzes trimethylation on lysine …
Diagnostic accuracy of nasopharyngeal swab, nasal swab and saliva swab samples for the detection of SARS-CoV-2 using RT-PCR
…, T Katsuno, Y Kusaba, K Sakamoto… - Infectious …, 2021 - Taylor & Francis
Background The current gold standard in coronavirus disease (COVID-19) diagnostics is
the real-time reverse transcription–polymerase chain reaction (RT-PCR) assay for detecting …
the real-time reverse transcription–polymerase chain reaction (RT-PCR) assay for detecting …
Polarizing agents beyond pentacene for efficient triplet dynamic nuclear polarization in glass matrices
K Sakamoto, T Hamachi, K Miyokawa… - Proceedings of the …, 2023 - National Acad Sciences
Triplet dynamic nuclear polarization (triplet-DNP) is a technique that can obtain high nuclear
polarization under moderate conditions. However, in order to obtain practically useful …
polarization under moderate conditions. However, in order to obtain practically useful …
Side effects and antibody titer transition of the BNT162b2 messenger ribonucleic acid coronavirus disease 2019 vaccine in Japan
T Izumo, N Kuse, N Awano, M Tone, K Sakamoto… - Respiratory …, 2021 - Elsevier
Background The coronavirus disease (COVID-19) has afflicted large populations worldwide.
Although vaccines aroused great expectations, their side effects on Japanese people and …
Although vaccines aroused great expectations, their side effects on Japanese people and …
Direct hemoperfusion using a polymyxin B‐immobilized polystyrene column for COVID‐19
…, M Suzuki, M Hashimoto, K Sakamoto… - Journal of clinical …, 2021 - Wiley Online Library
Objective To evaluate the efficacy and safety of direct hemoperfusion using a polymyxin B‐immobilized
polystyrene column (PMX‐DHP) in severe acute respiratory syndrome …
polystyrene column (PMX‐DHP) in severe acute respiratory syndrome …
Meteorological parameters contributing to variability in 222Rn activity concentrations in soil gas at a site in Sapporo, Japan
R Fujiyoshi, K Sakamoto, T Imanishi… - Science of the total …, 2006 - Elsevier
Continuous 222 Rn monitoring in soil gas since November 22, 2004 has revealed variability
in activity concentration with time in the semi-natural woods on the campus of Hokkaido …
in activity concentration with time in the semi-natural woods on the campus of Hokkaido …
Sarcopenia, but not visceral fat amount, is a risk factor of postoperative complications after major hepatectomy
T Higashi, H Hayashi, K Taki, K Sakamoto… - International journal of …, 2016 - Springer
Background Major hepatectomy is associated with significant morbidity and mortality rates,
particularly in patients aged more than 70 years. This study assessed whether physical …
particularly in patients aged more than 70 years. This study assessed whether physical …
[HTML][HTML] Corticosteroids for hospitalized patients with mild to critically-ill COVID-19: a multicenter, retrospective, propensity score-matched study
S Ikeda, T Misumi, S Izumi, K Sakamoto, N Nishimura… - Scientific reports, 2021 - nature.com
Corticosteroids use in coronavirus disease 2019 (COVID-19) is controversial, especially in
mild to severe patients who do not require invasive/noninvasive ventilation. Moreover, many …
mild to severe patients who do not require invasive/noninvasive ventilation. Moreover, many …
[HTML][HTML] Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells
S Nakagawa, Y Sakamoto, H Okabe… - Oncology …, 2014 - spandidos-publications.com
Enhancer of zeste homolog 2 (EZH2) is involved in malignant transformation and the biological
aggressiveness of several human malignancies. Growing evidence indicates that EZH2 …
aggressiveness of several human malignancies. Growing evidence indicates that EZH2 …