COVID-19 does not lead to a “typical” acute respiratory distress syndrome

L Gattinoni, S Coppola, M Cressoni… - American journal of …, 2020 - atsjournals.org
In summary, we found that hypercapnia was common in patients with COVID-19–associated
ARDS while using low VT ventilation. VR was increased in these patients, which reflected …

Management of COVID-19 respiratory distress

JJ Marini, L Gattinoni - Jama, 2020 - jamanetwork.com
Acute respiratory distress syndrome (ARDS) can originate from either the gas or vascular
side of the alveolus. Although the portal for coronavirus disease 2019 (COVID-19) is …

[HTML][HTML] COVID-19 pneumonia: different respiratory treatments for different phenotypes?

L Gattinoni, D Chiumello, P Caironi, M Busana… - Intensive care …, 2020 - Springer
The Surviving Sepsis Campaign panel recently recommended that “mechanically ventilated
patients with COVID-19 should be managed similarly to other patients with acute respiratory …

Anemia and blood transfusion in critically ill patients

JL Vincent, JF Baron, K Reinhart, L Gattinoni, L Thijs… - Jama, 2002 - jamanetwork.com
ContextAnemia is a common problem in critically ill patients admitted to intensive care units (ICUs),
but the consequences of anemia on morbidity and mortality in the critically ill is …

[HTML][HTML] A trial of goal-oriented hemodynamic therapy in critically ill patients

L Gattinoni, L Brazzi, P Pelosi, R Latini… - … England Journal of …, 1995 - Mass Medical Soc
Background Hemodynamic therapy to raise the cardiac index and oxygen delivery to
supranormal levels may improve outcomes in critically ill patients. We studied whether increasing …

[HTML][HTML] Effect of prone positioning on the survival of patients with acute respiratory failure

L Gattinoni, G Tognoni, A Pesenti… - … England Journal of …, 2001 - Mass Medical Soc
Background Although placing patients with acute respiratory failure in a prone (face down)
position improves their oxygenation 60 to 70 percent of the time, the effect on survival is not …

Pressure-volume curve of total respiratory system in acute respiratory failure: computed tomographic scan study

L Gattinoni, A Pesenti, L Avalli, F Rossi… - American Review of …, 1987 - atsjournals.org
To investigate the relationship between lung anatomy and pulmonary mechanics in acute
respiratory failure (ARF), 20 patients with ARF underwent computerized tomography (CT) at 3 …

The concept of “baby lung”

L Gattinoni, A Pesenti - Applied Physiology in Intensive Care Medicine 1 …, 2012 - Springer
Background: The “baby lung” concept originated as an offspring of computed tomography
examinations which showed in most patients with acute lung injury/acute respiratory distress …

Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome

…, M Quintel, AS Slutsky, L Gattinoni… - American journal of …, 2007 - atsjournals.org
Rationale: Tidal volume and plateau pressure limitation decreases mortality in acute
respiratory distress syndrome. Computed tomography demonstrated a small, normally aerated …

The American–European Consensus Conference on ARDS, part 2: ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to …

…, J Carlet, D Dreyfuss, L Gattinoni… - American journal of …, 1998 - atsjournals.org
The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity
and mortality of patients in intensive care units throughout the world, imparting tremendous …