Like other body districts, lungs present a complex bacteria community. An emerging function
of lung microbiota is to promote and maintain a state of immune tolerance, to prevent …

Simple Summary Tumor stroma is known to significantly influence cancer initiation and
progression. In the last decade, 3D cell cultures have shown potential in modeling the tumor …

Immune checkpoint inhibitors (ICIs) have made a breakthrough in the treatment of different
types of tumors, leading to improvement in survival, even in patients with advanced cancers. …

… M. Garassino reports receiving commercial research grants from MSD, speakers bureau
honoraria from Bristol-Myers Squibb, MSD, Roche, and AstraZeneca, and is a consultant/…

Non-commercial use only Page 1 Introduction On February 2020, Italy, especially the northern
regions, was hit by an epidemic of the new SARS-Cov-2 coronavirus that spread from …

… manufacturing of T cells; SD, JDH, YJ, and LG performed flow cytometry and intracellular
cytokine staining; M. Sommariva performed microarray analysis, cytokine release; YJ and M. …

Variegated decomposers: The synthesis of the first mixed alkali metal borohydride, which
contains lithium and potassium, is presented. LiK(BH 4)2 (see picture; K crimson, Li yellow, B …

In sites of inflammation or tissue injury, hyaluronic acid (HA), ubiquitous in the extracellular
matrix, is broken down into low mw HA (LMW-HA) fragments that have been reported to …

Objective: To assess whether a systematic approach to weaning and extubation (intervention)
is superior to the sole physician’s judgment (control) in preventing reintubation secondary …

Background: Adoptive therapy with tumour-infiltrating lymphocytes (TILs) induces durable
complete responses (CR) in∼ 20% of patients with metastatic melanoma. The recruitment of T …