Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts

…, N Murase, PF Drain, X Wang, M Sasidhar… - The Journal of …, 2006 - rupress.org
Carbon monoxide (CO), a byproduct of heme catabolism by heme oxygenase (HO), confers
potent antiinflammatory effects. Here we demonstrate that CO derived from HO-1 inhibited …

[HTML][HTML] Exhaled breath analysis with a colorimetric sensor array for the identification and characterization of lung cancer

…, J Na, JW Kemling, KS Suslick, M Sasidhar - Journal of Thoracic …, 2012 - Elsevier
Introduction The pattern of exhaled breath volatile organic compounds represents a
metabolic biosignature with the potential to identify and characterize lung cancer. Breath …

Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium

X Zhang, P Shan, M Sasidhar, GL Chupp… - American journal of …, 2003 - atsjournals.org
Therapy with high oxygen concentrations (hyperoxia) is often necessary to treat patients
with respiratory failure. However, hyperoxia may exacerbate the development of acute lung …

[HTML][HTML] The effect of metformin and thiazolidinedione use on lung cancer in diabetics

…, H Rai, M Beukemann, M Xu, A Jain, M Sasidhar - BMC cancer, 2012 - Springer
Background Metformin and the thiazolidinediones (TZDs) may have a protective effect
against the development of lung cancer. Methods Patients with diabetes mellitus (DM) were …

[PDF][PDF] Caring for VIPs: nine principles

JA Guzman, M Sasidhar, JK Stoller - Cleve Clin J Med, 2011 - researchgate.net
. ABSTRACT Caring for very important persons (VIPs), including celebrities and royalty,
presents medical, organizational, and administrative challenges, often referred to collectively as …

[HTML][HTML] Surgical oncologists and the COVID-19 pandemic: guiding cancer patients effectively through turbulence and change

…, SK Libutti, JA Margenthaler, M Sasidhar… - Annals of surgical …, 2020 - Springer
Background The COVID-19 pandemic has posed extraordinary demands from patients,
providers, and health care systems. Despite this, surgical oncologists must maintain focus on …

Noninferiority of inhaled epoprostenol to inhaled nitric oxide for the treatment of ARDS

…, SR Bauer, SN Bass, M Sasidhar… - Annals of …, 2015 - journals.sagepub.com
Background: Inhaled nitric oxide and inhaled epoprostenol have been evaluated for the
management of hypoxemia in acute respiratory distress syndrome, with clinical trials …

Tidal volume variability during airway pressure release ventilation: case summary and theoretical analysis

M Sasidhar, RL Chatburn - Respiratory care, 2012 - rc.rcjournal.com
Airway pressure-release ventilation (APRV) is used in the management of patients with severe
or refractory respiratory failure. In addition to reversal of inspiratory-expiratory ratios, this …

Inhaled epoprostenol through noninvasive routes of ventilator support systems

MA Ammar, M Sasidhar… - Annals of …, 2018 - journals.sagepub.com
Background: The administration of inhaled epoprostenol (iEPO) through noninvasive routes
of ventilator support systems has never been previously evaluated. Objective: Describe the …

Characteristics and outcomes of patients with lung transplantation requiring admission to the medical ICU

…, O Akindipe, MM Budev, XF Wang, M Sasidhar - Chest, 2014 - Elsevier
BACKGROUND There are few data on characteristics and outcomes among patients with
lung transplantation (LT) requiring admission to the medical ICU (MICU) beyond the …