Introduction Fever is frequently observed in critically ill patients. An independent association
of fever with increased mortality has been observed in non-neurological critically ill patients …

Background The joint committee of the Japanese Society of Intensive Care Medicine/Japanese
Respiratory Society/Japanese Society of Respiratory Care Medicine on ARDS Clinical …

Importance Obesity, diabetes, and hypertension are common comorbidities in patients with
severe COVID-19, yet little is known about the risk of acute respiratory distress syndrome (…

Purpose In many countries, patients are generally allowed to have clear fluids until 2–3 h
before surgery. In Japan, long preoperative fasting is still common practice. To shorten the …

Background Little evidence supports anticoagulant therapy as effective adjuvant therapy to
reduce mortality overall in sepsis. However, several studies suggest that anticoagulant …

Recombinant human soluble thrombomodulin (rhTM) is a novel class of anticoagulants for
treating disseminated intravascular coagulation (DIC). Although rhTM is widely used in …

Background The Japanese Society of Respiratory Care Medicine and the Japanese Society
of Intensive Care Medicine provide here a clinical practice guideline for the management of …

Purpose We investigated the epidemiology and outcome of disseminated intravascular
coagulation (DIC) in patients with sepsis. Materials and methods We analyzed data from a …

Background Although acute kidney injury (AKI) is known as a serious complication after
operation for acute type A aortic dissection (AAAD), the long-term impact of AKI remains unclear. …

Supplemental doses of antithrombin (AT) are widely used to treat sepsis-induced disseminated
intravascular coagulation (DIC) in Japan. However, evidence on the benefits of AT …