Rationale: It is commonly stated that mortality from acute respiratory distress syndrome (ARDS)
and acute lung injury (ALI) is decreasing. Objectives: To systematically review the …

Rationale: Recent literature in mechanical ventilation includes strong evidence from
randomized trials. Little information is available regarding the influence of these trials on usual …

The COVID-19 pandemic has seen a surge of patients with acute respiratory distress syndrome
(ARDS) in intensive care units across the globe. As experience of managing patients …

The article focuses on the issues regarding the reliability and validity of the acute respiratory
distress syndrome (ARDS) definition which was discussed in the 1994 American-European …

Background The efficacy of venovenous extracorporeal membrane oxygenation (ECMO) in
patients with severe acute respiratory distress syndrome (ARDS) remains controversial. …

Purpose Our objective was to revise the definition of acute respiratory distress syndrome (ARDS)
using a conceptual model incorporating reliability and validity, and a novel iterative …

Background: This document provides evidence-based clinical practice guidelines on the use
of mechanical ventilation in adult patients with acute respiratory distress syndrome (ARDS). …

Background The need for reintubation after extubation and discontinuation of mechanical
ventilation is not uncommon and is associated with increased mortality. Noninvasive positive-…

Background Previous trials suggesting that high-frequency oscillatory ventilation (HFOV)
reduced mortality among adults with the acute respiratory distress syndrome (ARDS) were …

Rationale: Baseline characteristics and management have changed over time in patients
requiring mechanical ventilation; however, the impact of these changes on patient outcomes is …